Fig. 4

WTAP expression was markedly elevated and mediated m6 A modification of LINC00200 in glioma cells. A WTAP expression was analyzed in glioma samples from the data obtained from TCGA database. B WTAP expression was detected in 28 glioma tissue samples and 28 adjacent healthy tissue samples via qRT-PCR. C The correlation of LINC00200 and WTAP expressions in glioma tissue samples was determined by Pearson correlation analysis. D The relative protein levels of WTAP were analysed in HS683 and T98G cells transfected with OE-NC, OE-WTAP, si-NC, and si-WTAP by western blotting. E The relative expression of LINC00200 was detected in HS683 and T98G cells by qRT-PCR at 48 h post-transfection with OE-NC, OE-WTAP, si-NC, and si-WTAP. F The status of m6 A methylation of LINC00200 between OE-NC and OE-WTAP transfected glioma cells was assessed using MeRIP-qPCR. G The status of m6 A methylation of LINC00200 between si-NC and si-WTAP transfected glioma cells was assessed using MeRIP-qPCR. **P < 0.001