Fig. 2

Silencing LINC00200 reduced the malignant properties of glioma cells in vitro and in vivo. A The relative expression of LINC00200 was detected in HS683 and T98G cells by qRT-PCR at 48 h post-transfection with si-NC, si-lnc#1 and si-lnc#2. B The CCK-8 assay was done to determine the cell viability in the two transfected glioma cell lines. C The colony formation assay was done to check the cell number in the two transfected glioma cell lines. D The transwell migration assay was performed to assess the migrative ability in the two transfected glioma cell lines. E The transwell invasion assay was conducted to check the invasive ability in the two transfected glioma cell lines. F Tumor volume, size, and weight in mice after injecting HS683 cells with the transfection of LV-NC (negative control of lentiviral vector) and LV-lnc (LINC00200 knockdown lentiviral vector). **P < 0.001 vs. si-NC or LV-NC