Fig. 9

METTL16 Knockdown in vivo suppressed tumor growth A Western blot analysis of overexpression efficiency of sh-METTL16 in Huh- 7/DDP cells. B Tumor volume statistics at 8 Day, 12 Days, 16 Days, 20 Days, 24 Days, and 28 Days after treatment with sh-NC + PBS, sh-NC + DDP, sh-METTL16 + PBS, sh-METTL16 + DDP. C Tumor weight analysis after treatment with sh-NC + PBS, sh-NC + DDP, sh-METTL16 + PBS, sh-METTL16 + DDP. D Western blot analysis of METTL16 in tumor tissues after treatment with sh-NC + PBS, sh-NC + DDP, sh-METTL16 + PBS, sh-METTL16 + DDP. E Western blot analysis of LAMA4 in tumor tissues after treatment with sh-NC + PBS, sh-NC + DDP, sh-METTL16 + PBS, sh-METTL16 + DDP. F Western blot analysis of COL4A1 in tumor tissues after treatment with sh-NC + PBS, sh-NC + DDP, sh-METTL16 + PBS, sh-METTL16 + DDP. G The expressions of METTL16, LAMA4, and COL4A1 were detected by IHC after treatment with sh-NC + PBS, sh-NC + DDP, sh-METTL16 + PBS, sh-METTL16 + DDP. *P < 0.05