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Fig. 5 | Cell Division

Fig. 5

From: METTL16/IGF2BP2 axis enhances malignant progression and DDP resistance through up-regulating COL4A1 by mediating the m6A methylation modification of LAMA4 in hepatocellular carcinoma

Fig. 5

m6A methylation of LAMA4 was regulated by IGF2BP2.A ENCORI database predicted the possible interaction between IGF2BP2 and LAMA4. B Correlation analysis of LAMA4 and IGF2BP2 in 374 samples from ENCORI database. C, D RIP assay of IGF2BP2 enrichment level after interference with METTL16 in Hep3B/DDP and Huh- 7/DDP cells. E Protein expression level of IGF2BP2 after transfection with si-IGF2BP2 in Hep3B/DDP and Huh- 7/DDP cells. F mRNA expression levels of LAMA4 after transfection with si-IGF2BP2 in Hep3B/DDP and Huh- 7/DDP cells. *P < 0.05

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Cell Division

ISSN: 1747-1028

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