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Fig. 1 | Cell Division

Fig. 1

From: METTL16/IGF2BP2 axis enhances malignant progression and DDP resistance through up-regulating COL4A1 by mediating the m6A methylation modification of LAMA4 in hepatocellular carcinoma

Fig. 1

METTL16 was up-regulated in HCC tissues and cells.A Protein expression of METTL16 in HCC normal samples (Normal, n = 165) and tumor samples (Primary tumor, n = 165) from CPTAC database. B METTL16 expression with 374 cancer and 50 normal samples in HCC samples from ENCORI database. C mRNA expression of METTL16 in sensitive tissues (n = 29) and resistant tissues (n = 33). D Protein expression of METTL16 in sensitive tissues (n = 3) and resistant tissues (n = 3). E IC50 values of Hep3B, Hep3B/DDP, Huh- 7, and Huh- 7/DDP cells. F Protein expression of METTL16 in THLE- 2, Hep3B, Hep3B/DDP, Huh- 7, and Huh- 7/DDP cells. *P < 0.05

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