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Fig. 4 | Cell Division

Fig. 4

From: YAP1 activates SLC2A1 transcription and augments the malignant behavior of colorectal cancer cells by activating the Wnt/β-catenin signaling pathway

Fig. 4

Overexpression of SLC2A1 restores malignant phenotype of CRC cells reduced by shYAP1.A, B qPCR and WB analyses of SLC2A1 levels in SW480 and Caco-2 cells; C CCK-8 assay assessing changes in cell viability; D EdU staining to evaluate the proliferative capacity; E Annexin-V/PI flow cytometry to assess the apoptotic ratio; F, G Transwell assays to evaluate the migratory and invasive capabilities. Cell experiments were repeated three to five times, and statistical analysis was performed using Two-Way ANOVA, **P < 0.01

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