Fig. 5

RFX2/RASSF1 axis activates the Hippo pathway. A Localization of RASSF1 in Hippo signaling cascades analyzed using the KEGG pathway database; B Expression of YAP and its phosphorylated proteins in A-549 and NCI-H358 cells were analyzed by WB; C Expression of YAP and its phosphorylated proteins in the oe-NC, oe-RFX2, oe-RFX2 + sh-NC, and oe-RFX2 + sh-RASSF1 groups were analyzed by WB. All cellular experiments were independently repeated 3 times. Single-factor comparisons among multiple groups were performed by one-way ANOVA (BC)