Fig. 1

Overexpression of RFX2 is identified in LUAD. A DEGs between 21 cases of NSCLC tissues and paired normal lung tissues in the GSE21933 dataset; B DEGs between tumor tissues of 80 LUAD patients who were smokers or non-smokers and normal lung tissues of those who never smoked in the GSE43458 dataset; C DEGs between 58 LUAD tissue and adjacent non-tumor tissue in the GSE32863 dataset; D Intersection of DEGs from GSE32863, GSE43458, and GSE21933 datasets, the first 2500 DEGs of LUAD in GEPIA, and human transcription factors obtained by Jvenn; E RFX2 expression in LUAD tissues and adjacent normal tissues was determined by IHC (n = 36); F, mRNA levels of RFX2 in LUAD tissue and adjacent normal tissue were determined by RT-qPCR (n = 36). Comparisons between 2 groups of a single factor were performed by t-test (EF)