Fig. 1

Expression of CCL3/CCR5 and the CD206 expression score of M2 macrophages in MM patients. A-B: CCL3 and CCR5 expression levels in BM were measured by ELISA (n = 37 MM patients and n = 15 healthy donors). C: Correlation between CCR5 and CCL3 expression levels. D: CD206 expression scores of M2 macrophages in BM tissues. E: mRNA expression levels of CCL3 in MM Bone Marrow (BM) samples measured by qRT-PCR. F: Correlation between CCL3 levels and the CD206 expression score. G: Representative images of CD206 + macrophage content in control and MM specimens by IHC staining (×200). (IHC, immunohistochemistry, *p < 0.05, **p < 0.01, ***p < 0.001)