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Fig. 5 | Cell Division

Fig. 5

From: Interaction of STIL with FOXM1 regulates SF3A3 transcription in the hepatocellular carcinoma development

Fig. 5

Combined knockdown of STIL and FOXM1 regulates SF3A3 transcription to suppress malignant behavior of HCC cells. (A) SF3A3 mRNA expression in HCC cells treated with KD-STIL + OE-NC or KD-STIL + OE-SF3A3 was assessed using RT-qPCR. Evaluation of cell proliferation using EdU assay (B) and colony formation assay (C) in Hep3B and Huh7 cells. (D) Detection of apoptosis using flow cytometry in Hep3B and Huh7 cells. Analysis of cell migration and invasion by wound healing assay (E) and Transwell invasion assay (F) in Hep3B and Huh7 cells. All data are expressed as mean ± SD from three experiments. In panels A-F, significance is determined by two-way ANOVA. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001

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Cell Division

ISSN: 1747-1028

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