Fig. 7
From: ZEB2 reduction contributes to pre-eclampsia via Wnt/β-Catenin pathway
Influence of AV939 and ZEB2-plasmid on preeclampsia-like symptoms in mice. PE mice were exposed to control-plasmid, ZEB2-plasmid and 10 µM XAV939. Mice were divided into five groups: C57 mice, PE mice, PE + control-plasmid, PE + ZEB2-plasmid, and PE + ZEB2-plasmid + XAV939 group. (A) Plot showing the SBP in different groups were measured. (B) Plot showing the urinary protein concentrations. (C-D) Relative mRNA levels of ZEB2 in the serum and placental tissues of PE mice. (E and F) Detection of ZEB2 protein expression in the placental tissues of PE mice. (G) TUNEL staining was applied to detect the apoptotic cells in the placental tissues of PE mice. **P < 0.01