Fig. 3

Effects of miR-5195-3p overexpression on CRC cell migration and invasion. (A) Representative images of wound healing (×200 amplification) and (B) quantification of relative migration distance was shown in transfected SW1116 and HT29 cells. (C) Representative images of transfected SW1116 and HT29 cell invasive ability. (D) Cell invasiveness was quantified by counting cells that passed through the Matrigel membrane, using a light microscope (×200). Scale bars, 100 μm; Data were expressed as means ± SD of three independent experiments. **p < 0.01, ***p < 0.001, compared with miR-NC