Fig. 1

The expression of miR-5195-3p was downregulated in CRC and associated with poor prognosis. (A) The expression level of miR-5195-3p was detected by quantitative real time PCR in tumor and adjacent tissues derived from CRC patients. p < 0.001, compared with adjacent tissues, t-test; (B) The expression level of miR-5195-3p was determined in CRC cell lines (SW1116 and HT29) and normal human colonic epithelial cells NCM460 by quantitative real time PCR. ***p < 0.001, compared with NCM460, one-way ANOVA followed by Dunnett’s test; (C) The Kaplan–Meier curves of overall survivals with high and low miR-5195-3p expressions