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Fig. 3 | Cell Division

Fig. 3

From: Extracellular vesicle-delivered hsa_circ_0090081 regulated by EIF4A3 enhances gastric cancer tumorigenesis

Fig. 3

Upregulated EIF4A3 in GC enriched hsa_circ_0090081. A circInteractome predicted the binding sites of EIF4A3 on the flanking sequences of the PHEX pre-mRNA transcript. B RIP assay revealed the coexistence of PHEX and EIF4A3 in the Ago-2 complex in AGS and HGC-27 cells. **P < 0.001 vs. IgG. C qRT-PCR revealed the EIF4A3 levels in human GC and normal samples. D Correlation between hsa_circ_0090081 and EIF4A3 in GC tissues. E Western blot showed the protein levels of EIF4A3 in AGS and HGC-27 treated with oe-NC and oe- EIF4A3. **P < 0.001 vs. oe-NC. F qRT-PCR revealed the hsa_circ_0090081 levels in AGS and HGC-27 treated with oe-NC and oe-EIF4A3. **P < 0.001 vs. oe-NC

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Cell Division

ISSN: 1747-1028

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