Fig. 6
From: SYVN1 modulates papillary thyroid carcinoma progression by destabilizing HMGB1
Overexpression of HMGB1 reverses PTC cell growth induced by SYVN1 in vivo. (A-C) Stable pcDNA3.1, pcDNA3.1-SYVN1 + vector, and pcDNA3.1-SYVN + HMGB1 transfected TPC-1 cells were injected subcutaneously into nude mice, and tumor lesions, volume, and weight were measured. (D) Representative IHC staining micrographs of Ki-67 and HMGB1 in tumor xenografts were conducted