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Fig. 5 | Cell Division

Fig. 5

From: Klotho-mediated activation of the anti-oxidant Nrf2/ARE signal pathway affects cell apoptosis, senescence and mobility in hypoxic human trophoblasts: involvement of Klotho in the pathogenesis of preeclampsia

Fig. 5

Klotho regulated cell viability, apoptosis, invasion and senescence in hypoxic human trophoblasts by regulating the Nrf2/ARE signal pathway. A, B The cell viability of human trophoblasts was determined by using the MTT assay. C Cell apoptosis in human trophoblasts was determined by using the apoptosis detection kit. D Transwell assay was performed to examine cell invasion abilities of human trophoblasts. E The cellular senescence-associated proteins (p16 and p21) were examined by performing Western Blot analysis. Each experiment was repeated at least for three times, and *P < 0.05 was considered as statistical significance. Each experiment was repeated at least for three times

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Cell Division

ISSN: 1747-1028

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