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Fig. 4 | Cell Division

Fig. 4

From: Klotho-mediated activation of the anti-oxidant Nrf2/ARE signal pathway affects cell apoptosis, senescence and mobility in hypoxic human trophoblasts: involvement of Klotho in the pathogenesis of preeclampsia

Fig. 4

Silencing of Nrf2 re-triggered oxidative damages in Klotho-overexpressed hypoxic human trophoblasts. A, B The regulating effects of Nrf2 knockdown on the expression levels of nuclear Nrf2, total Nrf2, SOD2 and NQO1 were determined by performing Western Blot analysis. C The MDA levels and D GSH/GSSG ratio in human trophoblasts were determined by using their corresponding kits. Each experiment was repeated at least for three times, and *P < 0.05 was considered as statistical significance. Each experiment was repeated at least for three times

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Cell Division

ISSN: 1747-1028

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