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Fig. 7 | Cell Division

Fig. 7

From: PPP2R2A inhibition contributes to preeclampsia by regulating the proliferation, apoptosis, and angiogenesis modulation potential of mesenchymal stem cells

Fig. 7

Influence of LY2940002 and PPP2R2A plasmid on dMSC proliferation, apoptosis, HTR-8/SVneo cell migration, and HUVEC tube formation. (A) MTT assay was performed to analyze dMSC proliferation. (B) dMSC apoptosis was assessed using FCM analysis. (C) Quantification of apoptotic dMSCs. (D) Western blot analysis of Bax and Bcl-2 expression. (E) mRNA levels of Bax and Bcl-2 were analyzed using RT-qPCR. (F) HTR-8/SVneo cell migration was analyzed using Transwell assay. (G) Migratory HTR-8/SVneo cells were calculated. (H) Tube formation of HUVEC was photographed under a microscope. (I) HUVEC tube formation assay was used to analyze HUVEC tube formation. N = 3. ** indicates P < 0.01 vs. control plasmid; ## indicates P < 0.01 vs. PPP2R2A plasmid

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Cell Division

ISSN: 1747-1028

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