Fig. 2

SGO1 downregulation reduces metastasis. Representative images for H&E staining of lung tissue are shown in low (top) and high (bottom) magnification (a). The black arrows point to metastasis (scale bars = 100 μm). The graph shows the number of mice that developed metastasis to the lungs (b). Representative images for H&E staining of liver tissue are shown in low (top) and high (bottom) magnification (c). The black arrows point to metastasis (scale bars = 100 μm). The graph shows the number of mice that developed metastasis to the liver (d). Graph showing tumor volume of secondary tumors (e). *p < 0.05, **p < 0.01, and ***p < 0.001 were considered statistically significant, while N.S. is non-significant. A Fisher Exact Test was used to compare differences between groups