Figure 3

IMAGe-mutants have decreased progression through S-phase after synchronization in S-phase. (A) Cell cycle analyses by flow cytometry of cells at T0 transfected as described in Figure 2A. (B) Immunoblot analysis of transfected cells showed a failure of accumulation of Cyclin-A, an S phase marker in IMAGe-mutant transfected cells at time T0.