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Figure 2 | Cell Division

Figure 2

From: The function of APC/CCdh1 in cell cycle and beyond

Figure 2

Cdh1 and cellular senescence. (A) Under normal conditions, the expression of p16 is tightly controlled by both positive and negative regulators. (B) Deletion of Cdh1 causes accumulation of Est2, leading to overexpression of p16 and senescence. (C) Oncogenic Ras may also induce senescence through Ets2.

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Cell Division

ISSN: 1747-1028

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